Optically active units for the synthesis of the side chain of (R

Details Optically active units for the synthesis of the side chain of (R Optically active units for the synthesis of the side chain of (R

1982-09-30

1985-05-21

Trousof, Natalie

Organic compounds -- part of the class 532-570 series

Organic compounds

Halogen containing

562602, 568841, 568878, 570101, 570181, 570252, 570257, 570261, C07C 1716, C07C 1726, C07C 1902

Patent

active

045188130

ABSTRACT:
(2R,6R)-1-Chloro-2,6,10-trimethyl-undecane I, (R)-(+)-.beta.-chloro-isobutyric acid II, (S)-(+)-1-bromo-3-chloro-2-methylpropane IV and (2R)-(+)-1-chloro-2,6-dimethyl-heptane V are novel optically active units for the synthesis of the side chain of (R,R,R)-.alpha.-tocopherol. In the process according to the invention, the optically active C.sub.14 -chloride I is obtained in 6 simple reaction steps starting from II, via the novel intermediates IV and V, in accordance with the following equation: ##STR1##

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