Optically active trans-2-aryl-1-cyclohexanol derivatives and a p

Chemistry: molecular biology and microbiology – Process of utilizing an enzyme or micro-organism to destroy... – Resolution of optical isomers or purification of organic...

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579421, 560129, 568 49, 568633, 568644, C07D31500, C07C 6900, C07C 4100

Patent

active

053957660

ABSTRACT:
The present invention provides an optically active trans-2-aryl-1-cyclohexanol derivative represented by the following general formula (I). ##STR1## The compounds can be obtained by transesterifiation reaction of the following compound (II) as a starting material with lipase. ##STR2## The optically active trans-2-aryl-1-cyclohexanol derivative can be used as an asymmetric source of asymmetric Diels-Alder reaction or a starting material of physiological active materials.

REFERENCES:
patent: 2130525 (1938-09-01), Coleman et al.
patent: 4400293 (1983-08-01), Romer et al.
patent: 4654162 (1987-03-01), Sugiwari et al.

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