Optically active substituted butyramide, and process for the opt

Details Optically active substituted butyramide, and process for the opt Optically active substituted butyramide, and process for the opt

1985-01-22

1989-03-14

Warren, Charles F.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing alpha or beta amino acid or substituted amino acid...

435280, 435141, 435212, 435863, 435228, C12P 1308, C12P 752, C07P 4100, C12N 948

Patent

active

048124036

ABSTRACT:
Process for preparing D-2-amino-2,3-dimethylbutyramide and/or L-2-amino-2,3-dimethylbutyric acid, wherein an aqueous solution of DL-2-amino-2,3-dimethylbutyramide is contacted with a preparation containing an aminoacyl amidase which has been obtained from a culture of Mycobacterium neoaurum and in that subsequently D-2-amino-2,3-dimethylbutyramide and/or L-2-amino-2,3-dimethyl-butyric acid is (are) recovered from the resulting hydrolysis mixture. The compound D-2-amino-2,3-dimethylbutyramide is novel.

REFERENCES:
patent: 3971700 (1976-07-01), Boesten
patent: 4080259 (1978-03-01), Boesten et al.
patent: 4443548 (1984-04-01), Oshima et al.
patent: 4481362 (1984-11-01), Nakai et al.
patent: 4497957 (1985-02-01), Nakai et al.
PCT Publication WO 80/01571, published Aug. 7, 1980, (w/English abstract).

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