Optically active, substituted 1,4-dihydropyridines and their use

Details Optically active, substituted 1,4-dihydropyridines and their use Optically active, substituted 1,4-dihydropyridines and their use

1986-12-12

1988-07-26

Fan, Jane T.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546278, 546279, 546270, C07D41304

Patent

active

047601477

ABSTRACT:
Optically active substituted 1,4-dihydropyridines of the formula I having calcium antogonistic properties: ##STR1## wherein R denotes alkyl with 1 to 5 C atoms, alkoxy-alkyl with 1 to 4 C atoms, in the alkoxy part and 2 to 4 C atoms in the alkyl part, dialkylaminioalkyl with a total of 3 to 6 C atoms each of the alkyl groups as substituents on the amino group having 1 to 3 C atoms, or --CH(CH.sub.3)CO.sub.2 R.sup.5 in the optically active (R)-forms,

REFERENCES:
patent: 4497808 (1985-02-01), Zimmermann et al.
patent: 4510310 (1985-04-01), Wehinger et al.
patent: 4532248 (1985-07-01), Franckowiak et al.
patent: 4551467 (1985-11-01), Wehinger et al.
patent: 4558058 (1985-12-01), Schonafinger et al.
patent: 4578467 (1986-03-01), Bonacchi et al.
Schramm et al., Nature, vol. 303, Jun. 9, 1983.

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