Optically active organic acidate-bridged dinuclear...

Details Optically active organic acidate-bridged dinuclear... Optically active organic acidate-bridged dinuclear...

2011-05-17

2011-05-17

Gonzalez, Porfirio Nazario (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heavy metal containing

C514S492000

Reexamination Certificate

active

07943793

ABSTRACT:
The present invention is an optically active organic acidate-bridged dinuclear platinum(II) complex represented by the general formula (I):or the general formula (I′):(wherein R1and R2are the same or different and each represent a hydrogen atom or an alkyl group, or form an alkylene group by binding to each other at the ends thereof;R3and R4are the same or different and each represent a hydrogen atom or an alkyl group, or form an alkylene group by binding to each other at the ends thereof;A represents a single bond or a methylene group; andX−represents an anion).The complex of the present invention has an excellent anticancer activity, and is useful as medicine, especially an anticancer agent.

REFERENCES:
English Translation of the International Preliminary Report on Patentability.
Y. Igawa et al., “Synthesis of Novel L-Tartrate-Bridged Dinuclear Copper(II) Complexes and Their Properties”, The 53rdSymposium, Japan Society of Coordination Chemistry, Abstracts, p. 11 (1Aa01), Sep. 10, 2003 along with its English translation.

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