Optically active N-hydroxy-alpha-amino acids, amides and their d

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

564160, 564198, 562556, 562557, 562561, 562567, 562568, 562575, 548344, 548496, C07C22908, C07C22936, C07C23706, C07C23720

Patent

active

050720414

ABSTRACT:
The invention relates to new pure D- or L-N-hydroxy-alpha-amino acids and the derivatives thereof, including optically active N-hydroxy-phenylglycine amide, which has antibiotic and antitumor activity.

REFERENCES:
patent: 3064007 (1962-11-01), Krimm et al.
patent: 4172846 (1979-10-01), Boesten
patent: 4847412 (1989-07-01), Boesten et al.
Grundke et al., Synthesis, (12), 1115-1116 (1987).
March, "Advanced Organic Chemistry", 2nd ed., McGraw-Hill, New York, 1977, p. 1107.
Polonski et al., I, Tetrahedron Letters, (28), 2453-56, (1974).
Polonski et al., II, Chemical Abstracts, vol. 93, No. 26754u (1980).
Polonski et al., III, Chemical Abstracts, vol. 90, No. 87876v (1979).
Chemical & Pharmaceutical Bulletin, vol. 28, No. 9, Sep. 1980, pp. 2720-2733, Pharmaceutical Society of Japan, Tokyo, JP; M. Mano et al.: "Anticoccidials. IV. A Convenient Synthesis of 2(1H)-Pyrazinone 4-oxide Derivatives".
Tetrahedron Letters, No. 28, Jul. 1974, pp. 2453-2456, Pergamon Press, Oxford, GB; T. Polonski et al.: "Oxidation of Amino Acid Esters into N-Hydroxy-Alpha-Amino Acids in Organic Chemistry".
Chemica Reviews, vol. 86, No. 4, Aug. 1986, pp. 697-700, American Chemical Society, U.S.; H. C. J. Ottenheijm et al.: "N-Hydroxy-Alpha-Amino Acids in Organic Chemistry".
E. Muller: "Methoden der Organischen Chemie", 4th edition, vol. X/4, 1968, pp. 409-410, (Houben-Weyl), Stuttgart, DE; W. Rundel: "Nitrone".
Pritzkow et al., Justus Liebigs Ann. Chem. 703, 66-76 (1967).
Willems et al., Chemical Abstracts, vol. 51, No. 17543e (1957).
Kaminski et al., Chemical Abstracts, vol. 79, No. 42819k (1973).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Optically active N-hydroxy-alpha-amino acids, amides and their d does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Optically active N-hydroxy-alpha-amino acids, amides and their d, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Optically active N-hydroxy-alpha-amino acids, amides and their d will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1042225

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.