Optically-active isomers of dideoxycarbocyclic nucleosides

Details Optically-active isomers of dideoxycarbocyclic nucleosides Optically-active isomers of dideoxycarbocyclic nucleosides

1994-08-15

1997-05-20

Tsang, Cecilia

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

544264, 544265, 544276, 544277, C07F 902, A61K 3152, C07D47330, C07D47332

Patent

active

056313705

ABSTRACT:
A therapeutic method is provided, employing an antiviral compound of the general formula: ##STR1## wherein Z is H, OR' or N(R).sub.2, wherein R' is H, (C.sub.1 -C.sub.4)alkyl, aryl, CHO, (C.sub.1 -C.sub.16)alkanoyl or O.dbd.P(OH).sub.2, Y is CH or N, and X is selected from the group consisting of H, N(R).sub.2, SR, OR' or halogen, wherein R is H, lower(C.sub.1 -C.sub.4)alkyl, aryl or mixtures thereof, and the pharmaceutically acceptable salts thereof.

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