Optically active hydroxybenzylamine

Details Optically active hydroxybenzylamine Optically active hydroxybenzylamine

1988-10-03

1991-04-30

Raymond, Richard L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

564 9, 564302, 564304, C07F 500

Patent

active

050119893

ABSTRACT:
The optically active benzylamine derivatives of the present invention are very useful for use as the asymmetric ligand of an asymmetric reducing agent. By using the optically active amine-boron complex prepared from the compound of the present invention, optically active products can be obtained in a specifically high optical yield. Moreover, the separation and recovery of the reaction products and asymmetric ligand can be easily achieved.

REFERENCES:
patent: 4000197 (1976-12-01), Barfknecht et al.
patent: 4749809 (1988-06-01), Yoneyashi et al.
patent: 4760149 (1988-07-01), Yoneyoshi et al.
J. Chem. Soc., Perkin Trans. I, 1985, 2039-2044, ITSUNO et al., "Asymmetric Synthesis Using Chirally Modified Boronhydrides. Part 3 . . ."
J. Org. Chem., vol. 37, No. 14, 1972, pp. 2347-2349, Borch et al., "An Asymmetric Synthesis of Alcohols, Amines, and Amino Acids".
Tretrhedron Letters, vol. 29, No. 2, pp. 223-224, 1988, Sakito et al. "Asymmetric Reduction of Oxime Ethers, Distinction of Anti and Syn Isomers".
J. Chem. Soc., vol. 99, 1911, pp. 416-421, Moore, "Alpha-p-Hydroxy-m-Methoxyphenylethylamine and the Resolution of . . .".

Affiliated with

Also associated with

Rating

Optically active hydroxybenzylamine does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Optically active hydroxybenzylamine, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Optically active hydroxybenzylamine will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-641633