Optically active, heteroaromatic β-hydroxy esters and...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Details

C548S179000, C548S180000, C548S237000, C548S304400

Reexamination Certificate

active

07626035

ABSTRACT:
The present invention relates to new optically active heteroaromatic β-hydroxy esters useful in the synthesis of epothilone derivatives, to certain compounds used to produce these intermediates, as well as to processes for their production.

REFERENCES:
patent: 2003/0144533 (2003-07-01), Iwasaki et al.
patent: 10041470 (2002-02-01), None
patent: WO 97/12884 (1997-04-01), None
patent: WO 98/54350 (1998-12-01), None
patent: WO 00/58254 (2000-10-01), None
Ratovelomanana-Vidal et al., “Enantioselective Hydrogenation of β-Keto Esters using Chiral Diphosphine-Ruthenium Complexes: Optimization for Academic and Industrial Purposes and Synthetic Applications,” Advanced Synthesis and Catalysts, Jan. 21, 2003, pp. 261-274, vol. 345, No. ½, XP002326558, the whole document.
Database CA ′Online! D'Alo, F. et al., “N-Alkylalkanolamines of the benzo'b!thiophene series,” 1965, Chemical Abstracts Service, Columbus, Ohio, US, XP002326559, retrieved from STN Database accession No. 1965:82375 RN: 1138-07-4, Benzo'b!thiophene-5-propionic acid,.beta.-oxo- abstract & Bollettino Chimico Farmaceutico, 1964, pp. 709-726, vol. 103, No. 10, Coden:BCFAAI; ISSN: 0006-6648.

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