Optically active fluorine-containing compound

Details Optically active fluorine-containing compound Optically active fluorine-containing compound

1992-12-11

1994-03-22

Chan, Nicky

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D30910

Patent

active

052966160

ABSTRACT:
There is disclosed an optically active fluorine-containing compound represented by the general formula (I) ##STR1## wherein Rf is a fluoroalkyl group having 1 or 2 carbon atoms; R.sup.1, R.sup.2 and R.sup.3, independently of one another, are each a hydrogen atom, a straight or branched chain alkyl group having 1 to 15 carbon atoms, an alkenyl group having 2 to 15 carbon atoms or an aralkyl group having 7 to 10 carbon atoms; and * is an asymmetric carbon atom. The above compound has a fluoroalkyl group with a remarkable electron-attracting property at the asymmetric carbon atom in the tetrahydropyran ring. It is exemplified by tetrahydro-6-trifluoromethyl-2-hexyloxy-4-methyl-5-hydroxypyran and expected to find a wide variety of useful applications as raw materials for an enzyme inhibitor, a bioactive substance, a carcinostatic, a ferroelectric liquid crystal, etc.

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