Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing
Patent
1991-10-03
1993-03-30
Robinson, Allen J.
Organic compounds -- part of the class 532-570 series
Organic compounds
Amino nitrogen containing
560 39, 560 40, 560 41, 564152, 564155, C07C23332, C07C22934
Patent
active
051985837
ABSTRACT:
The optically active antiviral compound [1R-(1.alpha., 2.beta., 3.alpha.)]-2-amino-9-[2,3-bis(hydroxymethyl)-cyclobutyl]-1,9-dihydro-6H-pu rin-6-one and novel intermediates useful in its preparation are described.
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Ichikawa et al., "Enantio and Diastereo-selective Synthesis . . . ", J. Chem. Soc., Chem Commun, 1989, pp. 1919-1921.
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M. Honjo, et al., Synthesis of the Carbocyclic Analogue of Oxetanocin A.sup.1, Chem. Pharm. Bull. 37(5) 1413-1415 (1989).
Y. Hayashi, et al., Asymmetric [2+2] Cycloaddition Reaction Catalyzed by a Chiral Titanium Reagent. Chemistry Letters, pp. 793-796 (1989).
W. Slusarchyk, et al., SQ33,054: A Potent Member of a New Class of Nucleosides-Analog Antivirals--Abstract No. 1330--XXIX Interscience on Antimicrobial Agents & Chemo., pp. 17-20, 1989, Houston, TX.
Oral report by the Japanese Company Nippon Kayaku, Gordon Research Conf., Jul. 24-28, 1989, New Hampton, NH.
W. Slusarchyk et al., Synthesis of SQ33,054, A Novel Cyclobutane Nucleoside with Potent Antiviral Activity; Tetrahedron Letters, vol. 30, p. 6453 (1989).
Bisacchi Gregory S.
Mitt Toomas
Davis Stephen B.
E. R. Squibb & Sons Inc.
Robinson Allen J.
Russell Mark W.
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