Optically active carbamates, process for preparation thereof...

Details Optically active carbamates, process for preparation thereof... Optically active carbamates, process for preparation thereof...

2006-12-08

2010-12-14

Wilson, James O (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C544S396000

Reexamination Certificate

active

07851627

ABSTRACT:
The present invention is related to 1-[(4-chlorophenyl)-phenylmethyl]-4-(2,2,2-trichloroethoxycarbonyl)-piperazine of the Formula (IV) and optically isomers thereof, process for preparation thereof and the use of the compound of the Formula (IV) in the preparation of 1-(4-chlorophenyl)-phenylmethyl-piperazine and optical isomers and salts thereof. 1-(4-chlorophenyl)-phenylmethyl-piperazine and optical isomers thereof are important intermediates in the preparation of non-sedating antihistamine-type active pharmaceutical ingredients.

REFERENCES:
patent: 2709169 (1955-05-01), Morren
patent: 5478941 (1995-12-01), Cossement
patent: 6803465 (2004-10-01), Kudo
patent: 508650 (1952-02-01), None
patent: 501277 (1952-08-01), None
patent: 2076403 (1981-12-01), None

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