Optically active beta-aminoalkoxyborane complex

Details Optically active beta-aminoalkoxyborane complex Optically active beta-aminoalkoxyborane complex

1997-04-29

1998-07-28

McKane, Joseph

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

564 8, C07D20708

Patent

active

057864853

ABSTRACT:
An optically active .beta.-aminoalkoxyborane complex of the formula (I): ##STR1## wherein R.sup.1 is C.sub.1 -C.sub.8 alkyl, C.sub.3 -C.sub.7 cycloalkyl, C.sub.7 -C.sub.11 aralkyl or C.sub.6 -C.sub.10 aryl, R.sup.2 is hydrogen, C.sub.1 -C.sub.8 alkyl, C.sub.3 -C.sub.7 cycloalkyl or C.sub.7 -C.sub.11 aralkyl, or R.sup.1 and R.sup.2 together form (CH.sub.2).sub.n wherein n is 3 or 4, and Ar is naphthyl, anthryl or phenanthryl, which may be substituted by from 1 to 3 substituents selected from the group consisting of halogen, nitro, C.sub.1 -C.sub.6 alkyl, C.sub.3 -C.sub.7 cycloalkyl, C.sub.2 -C.sub.6 alkenyl, C.sub.2 -C.sub.6 alkynyl, C.sub.7 -C.sub.11 aralkyl, C.sub.6 -C.sub.10 aryl, C.sub.1 -C.sub.6 alkoxy and styrene polymer substituents.

REFERENCES:
patent: 4897490 (1990-01-01), Sit et al.
patent: 5552548 (1996-09-01), Quallich
patent: 5663348 (1997-09-01), Kashihara et al.
T. R. Govindachari et al., "Chemical Examination of Tylophora Asthmatica-IV.sup.1 Synthesis of Tylophorine.sup.2 ", Tetrahedron, vol. 14, pp. 284-287, 1961.
B. Chauncy et al., "Synthesis of Phenanthroindolizidines. II Synthesis of (+-)-Tylocrebine, (+-)-Tylophorine, (+-)-Antofine, and (+-)-2,3-Dimethoxyphenanthroindolizidine", Chemical Abstracts, Abstract No. 13313g, vol. 74, No. 3, 18 Jan. 1971.
B. Chauncy et al., "Synthesis of Phenanthroindolizidine", Chemical Abstracts, Abstract No. 88024q, vol. 70, No. 19, 12 May 1969.
H. Hashizume et al., "Resolution of D, L-Pantolactone", Chemical Abstracts, Abstract No. 38872p, vol. 110, No. 5, 30 Jan. 1989.
E. J. Corey et al., "Enantioselective Route To A Key Intermediate In The Total Synthesis of Ginkgolide B", Tetrahedron Letters, vol. 29, No. 26, pp. 3201-3204, 1988.
Takeshi Hanamoto et al., "A Facile Entry To .beta.,.delta.-Diketo And Syn-.beta.,.delta.-Dihydroxy Esters", Tetrahedron Letters, vol. 29, No. 49, pp. 6467-6470, 1988.
M. Cegla, "Chiral N-(Arylalkyl)-2-Amino-1-Butanol Derivatives As Stereoselective Reduction Agents Of Ketones", Chemical Abstracts, Abstract No. 39327q, vol. 107, No. 5, 3 Aug. 1987.
Chemical Abstracts, vol. 70, Jul. 23, 1969, p. 368, An-88024q.
Chemical Abstracts, vol. 74, Feb. 23, 1971, p. 326, AN-13313g.
Chemical Abstracts, vol. 107, Aug. 13, 1987, AN-39327q.
Chemical Abstracts, vol. 110, Feb. 17, 1989, AN38872p.
Tetrahedron, vol. 14, 1961, pp. 284-287, T.R. Govindachari et al., "Chemical Examination of Tylophora Asthmatica-IV".
Aust. J. Chem., vol. 22, pp. 427-429, 1969, B. Chauncy et al., "A New Synthesis Of Phenanthroindolizidine".
Aust. J. Chem., vol. 23, pp. 2503-2516, 1970, B. Chauncy et al., "Synthesis Of Phenanthroindolizidines".

Affiliated with

Also associated with

Rating

Optically active beta-aminoalkoxyborane complex does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Optically active beta-aminoalkoxyborane complex, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Optically active beta-aminoalkoxyborane complex will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-24649