Optically active and racemic hydrated diacetylesters of .alpha.-

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...

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558169, A61K 31685, C07F 910

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active

052159736

ABSTRACT:
Monohydrate 1,2-di-O-acetyl-glycero-phosphoryl-choline in optically active and racemic form, processes for their preparation and pharmaceutical compositions containing them as the active principle for treating cerebral involutions of the aged and for treating dislipidemia and hyperlipoproteinemia.

REFERENCES:
patent: 3687932 (1972-08-01), Nakamachi et al.
patent: 4607046 (1986-08-01), Morita et al.
Robert H. Pearson, "The Molecular Structure of Lecithin Dihydrate", Nature vol. 281 pp. 499-501, 1987.
N. H. Phuong, et al. "Chimie Organique". C.R. Acad. Sc. Paris vol. 283, pp. 323-325, 1976.
N. H. Phuong, et al. "Chimie Organique". C.R. Acad. Sc. Paris vol. 283, pp. 229-231, 1976.
Etsuo Hasegawa, et al. "A Convenient Synthesis of Mixed-Acid Glycerophosphocholines". Journal of Synthetic Organic Chemistry No. 1, pp. 60-62, 1986.

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