Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-05-06
1999-08-03
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
544250, A61K 31505, C07D48704
Patent
active
059325844
ABSTRACT:
This invention relates to novel optically active 3-substituted This invention also relates to the therapeutical use of these novel compounds ##STR1## wherein: R is halogen, hydrogen, methoxy, trifluoromethyl, C.sub.1 -C.sub.4 alkyl, nitro, acetyl, cyano or hydroxy group; or pharmaceutically acceptable salts thereof.
REFERENCES:
patent: 5340814 (1994-08-01), Chern et al.
patent: 5371080 (1994-12-01), Hansen et al.
patent: 5512677 (1996-04-01), Chern et al.
Maryam Zakerinia, Hady Davary and Gholam H. Hakimelahi, "The Syntheses of Purine and Pyrimidine Secoribo-nucleosides: Acyclo-uridine Derivative of Cyclophosphamide," Helvetica Chimica Acta, vol. 73, 1990, pp. 912-915.
R.A. Johnson, "Encyclopedia of Reagents for Organic Synthesis," 1995, vol. 4, pp. 2609-2613.
Jun-ichi Imagawa and Kazushige Sakai, "Further Evaluation of the Selectivity of a Novel Antihypertensive Agent, SGB-1534, for Peripheral .varies..sub.1 -adrenoceptors in the Spinally Anesthetized Dog," European Journal of Pharmacology, 1986, pp. 257-264.
Ji-Wang Chern, Pao-Luh tao, Mao-Hsiung Yen, Guan-Yu Lu, Chia-Yang Shiau, Yue-Jun Lai, Su-Lan Chien and Chao-Han Chan, "Studies on Quinazolines, 5.1 and Selective .varies..sub.1 -Adrenoceptor Antagonists and Antihypertensive Agents," J. Med. Chem. 1993, pp. 2196-2207.
Oyo Mitsunobu, "The Use of Diethyl Azodicarboxylate and Triphenylphosphine in Synthesis and Transformation of Natural Products," 1981, pp. 1-28.
Ji-Wang Chern, et al., Studies on Quinazolines. 6. Asymmetric Synthesis of (S)-(+)- and 1641-1648, Jun. 1996.
Chern Ji-Wang
Gutcait Alexander
Liu Hsiu-Wen
Wang Kuang-Chao
National Science Council
Raymond Richard L.
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