Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Patent
1982-06-11
1985-09-03
Killos, Paul J.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
560100, 560105, 560 9, 260456R, 556441, 568323, 568591, C07C 6976
Patent
active
045394202
ABSTRACT:
A manufacturing method is described for the preparation of optically active 1-aromatic-group-substituted-1-alkanones characterized in that an optically active alkane acid halide is allowed to react with an aromatic compound in the presence of a Lewis acid. The optically active 1-aromatic-group-substituted-1-alkanones are useful intermediates in the preparation of optically active alpha-arylalkanoic acids, which are useful as pharmaceutical, e.g. anti-inflammatory, analgesic and anti-pyretic, agents and as insecticidal agents.
Kitajima Koji
Mitamura Shuichi
Tsuchihashi Gen-Ichi
Dhuey John A.
Hirsch Joseph I.
Killos Paul J.
Syntex Pharmaceuticals International Limited
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