Optically active 1-(6-methoxy-2-naphthyl)-2-(alkoxycarbonyl) ami

Details Optically active 1-(6-methoxy-2-naphthyl)-2-(alkoxycarbonyl) ami Optically active 1-(6-methoxy-2-naphthyl)-2-(alkoxycarbonyl) ami

1983-03-28

1985-01-29

Helfin, Bernard

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

562444, 560 56, 564393, 549347, 549373, 549452, C07C125067, C07C12502

Patent

active

044967551

ABSTRACT:
A manufacturing method is described for the preparation of optically active 1-(6-methoxy-2-naphthyl)-2-(alkoxycarbonyl)amino-1-propanone, its derivatives and their halo analogs. The optically active 1-(6-methoxy-2-naphthyl)-2-(alkoxycarbonyl)amino-1-propanone, its derivatives and their halo analogs are useful intermediates in the preparation of 2-(6-methoxy-2-naphthyl)propionic acid, which is useful as pharmaceutical, e.g. antiinflammatory, analgesic and anti-pyretic agents.

REFERENCES:
Harrison et al., J. Med. Chem., 13, 203 (1970).

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