Optically active 1,2-bis-(diphenylphosphine)-compounds

Details Optically active 1,2-bis-(diphenylphosphine)-compounds Optically active 1,2-bis-(diphenylphosphine)-compounds

1980-12-31

1982-10-26

Sneed, Helen M. S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Phosphorus containing

252431P, 260429R, C07F 950

Patent

active

043563244

ABSTRACT:
The invention is directed to optically active 1,2-bis-(diphenylphosphino)-compounds of the general formula ##STR1## where Ph is a phenyl group and R is a straight or branched chain alkyl group with 2 to 20 carbon atoms or a benzyl group. Especially preferred are compounds in which R is an isopropyl or a benzyl group. These compounds can serve as chiral ligands in noble metal complexes, especially in rhodium complexes, which can be used as catalysts for the homogeneous asymmetrical hydrogenation of pro-chiral unsaturated compounds.

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patent: 4201714 (1980-05-01), Hughes
patent: 4294989 (1981-10-01), Knowles et al.
Brown et al., Tetrahedron Letters, No. 50, pp. 4859-4862 (1979).
Frysuk, Jour. Amer. Chem. Soc., vol. 100, Aug. 16, 1978, pp. 5491-5494.
King, Jour. Org. Chem., vol. 44, No. 10, pp. 1729-1731 (1979).

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