Optical waveguide type antibody chip and method of measuring...

Details Optical waveguide type antibody chip and method of measuring... Optical waveguide type antibody chip and method of measuring...

2008-03-13

2010-11-09

Chin, Christopher L (Department: 1641)

Chemistry: molecular biology and microbiology

Apparatus

Including measuring or testing

C385S012000, C385S129000, C385S130000, C422S051000, C422S082050, C422S082110, C435S288700, C435S808000, C436S164000, C436S165000, C436S524000, C436S527000, C436S805000, C436S807000

Reexamination Certificate

active

07829327

ABSTRACT:
An optical waveguide type antibody chip includes a transparent substrate, an incident-side optical element and an emitting-side optical element placed at a distance from each other on a primary face of the substrate, a water repellent resin film formed on the primary face of the substrate including an optical waveguide layer formed between the optical elements, the water repellent resin film includes a reaction hole having exposed the optical waveguide layer on its bottom and a frame-shaped trench surrounding the reaction hole, a rectangular frame-shaped cell wall which is fixed in the trench of the water repellent resin film and which forms a cell capable of infusion and discharge of a specimen solution together with the reaction hole, and an antibody immobilization layer formed on the bottom of the reaction hole, the surface of the antibody immobilization layer being masked with at least a buffer agent and a salt.

REFERENCES:
patent: 6469785 (2002-10-01), Duveneck et al.
patent: 3-7270 (1991-02-01), None

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