Optical tensor imaging

Surgery – Diagnostic testing – Detecting nuclear – electromagnetic – or ultrasonic radiation

Reexamination Certificate

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Details

C600S476000, C600S407000, C600S310000

Reexamination Certificate

active

07471975

ABSTRACT:
A method of measuring local and propagating pulsatile behavior of a vasculature system provides a way to non-invasively measure vascular dynamics and, in particular, allows for objective measurement of the propagating expansion-contraction waves. The method includes capturing a time-series of optical images, and analyzing the images to produce a time-series of vector field maps based on measurements of local displacement of hemoglobin contrast. The method further includes obtaining a resulting time-dependent tensor field image and analyzing the resulting time-dependent tensor field image to obtain metrics of local and propagating oscillatory behavior.

REFERENCES:
patent: WO 01/20305 (2001-03-01), None
Taylor, Charles A. et al. “In Vivo Quantification of Blood Flow and Wall Shear Stress in the Human Abdominal Aorta During Lower Limb Exercise”, Annals of Biomedical Engineering, vol. 30, p. 402-408, 2002.
Day, Steven W. et al. “Particle Image Velocimetry Measurements of Blood Velocity in a Continuous Flow Ventricular Assist Device”, ASAIO Journal, vol. 47(4), pp. 406-411, Jul.-Aug. 2001.

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