Optical structures for metal-enhanced sensing

Details Optical structures for metal-enhanced sensing Optical structures for metal-enhanced sensing

2006-07-18

2008-07-15

Geisel, Kara E (Department: 2877)

Optics: measuring and testing

By dispersed light spectroscopy

With sample excitation

C356S445000, C385S012000

Reexamination Certificate

active

07400397

ABSTRACT:
The present invention is directed to optical structures and methods detecting the fluorescence of a molecule using metal-enhanced fluorescence. In particular, the invention describes the use of surface plasmon excitation for excitation of fluorophores near the metal surface and the efficient collection of the emission by coupling into the plasmon resonance and directing towards the detector. More particularly, the present invention makes use of the unique directionality of the plasmon induced fluorescence signal. The present invention is directed to optical structures using metal enhanced fluorescence including: an optical fiber having a conductive external coating; a light emitting diode (LED) having a conical shaped depression with curved sides on a front end surface, the curved sides having a conducting coating on the outer surface with respect to the LED.

REFERENCES:
patent: 4649280 (1987-03-01), Holland et al.
patent: 4844869 (1989-07-01), Glass
patent: 5359681 (1994-10-01), Jorgenson et al.
patent: 5485277 (1996-01-01), Foster
patent: 5830766 (1998-11-01), Attridge et al.
patent: 6272262 (2001-08-01), Kopelman et al.
patent: 6361190 (2002-03-01), McDermott
patent: 6487326 (2002-11-01), Pantano et al.
patent: 6558958 (2003-05-01), Pilevar et al.
patent: 07-07184 (1995-01-01), None
Lakowicz, “Radiative Decay Engineering: Biophysical and Biomedical Applications,”Anal. Biochem., vol. 298, (2001), pp. 1-24.
Lakowicz et al., “Radiative Decay Engineering: 2. Effects of Silver Island Films on Fluorescence Intensity, Lifetimes and Resonance Energy Transfer,”Anal. Biochem., vol. 301, (2002), pp. 261-277.

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