Optical resolution of (.+-.)-2-(4-isobutylphenyl)-propionic acid

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

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562402, 562493, 564304, C07B 5700

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active

053211545

ABSTRACT:
(.+-.)-2-(4-Isobutylphenyl)-propionic acid can be resolved into optically active isomers easily and with high yields. The method is characterized by the use of the optically active amine of the following general formula (I) or (II) as a resolving agent. ##STR1##

REFERENCES:
patent: 4209638 (1980-06-01), Nicholson et al.
patent: 4723033 (1988-02-01), Erickson
patent: 4752417 (1988-06-01), Inoue et al.
patent: 4983765 (1991-01-01), Lukas et al.
patent: 5015764 (1991-05-01), Manimaran et al.
Patent Abstracts of Japan, vol. 10, No. 383, Dec. 23, 1986.

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