Chemistry: analytical and immunological testing – Optical result – With reagent in absorbent or bibulous substrate
Patent
1996-10-10
2000-12-26
Ludlow, Jan
Chemistry: analytical and immunological testing
Optical result
With reagent in absorbent or bibulous substrate
436172, 436175, 436530, 436533, G01N 128
Patent
active
061657980
ABSTRACT:
Methods for measuring the amount of an analyte in a membrane, by applying to the membrane a clearing agent, are disclosed. The clearing agent can be an agent that has approximately the same refractive index as the membrane; alternatively, the clearing agent can be a dissolving agent, that dissolves the membrane. The analyte can be labelled to facilitate detection. Representative labels include fluorescent labels and detectable particles.
REFERENCES:
patent: 3604929 (1971-09-01), Goulin
patent: 3899610 (1975-08-01), Henry
patent: 4001139 (1977-01-01), Long
patent: 4401765 (1983-08-01), Craig et al.
patent: 4521522 (1985-06-01), Lundstrom et al.
patent: 4690907 (1987-09-01), Hibino et al.
patent: 4703017 (1987-10-01), Campbell et al.
patent: 4703018 (1987-10-01), Craig et al.
patent: 4855240 (1989-08-01), Rosenstein et al.
patent: 4868131 (1989-09-01), Hiratsuka
patent: 4975366 (1990-12-01), Sudo et al.
patent: 5012681 (1991-05-01), Lentzen
patent: 5019496 (1991-05-01), Oster et al.
patent: 5030558 (1991-07-01), Litman et al.
patent: 5039607 (1991-08-01), Skold et al.
patent: 5096837 (1992-03-01), Fan et al.
patent: 5156952 (1992-10-01), Litman et al.
patent: 5164294 (1992-11-01), Skold et al.
patent: 5187083 (1993-02-01), Mullis
patent: 5232835 (1993-08-01), Litman et al.
patent: 5238652 (1993-08-01), Sun et al.
patent: 5248619 (1993-09-01), Skold et al.
patent: 5252696 (1993-10-01), Laas et al.
patent: 5266497 (1993-11-01), Imai et al.
patent: 5334513 (1994-08-01), Skold et al.
patent: 5401667 (1995-03-01), Koike
patent: 5434051 (1995-07-01), Allard et al.
patent: 5451507 (1995-09-01), Skold et al.
patent: 5468647 (1995-11-01), Skold et al.
Database CAPLUS, Abstract No. 1987:72555, Kasahara et al., Anal. Chem., 59(5), 787-9, 1987.
Webster's Ninth New Collegiate Dictionary, Merriam-Webster Inc. p. 1254, 1987.
Hierholzer, J.C. et al., "Spectrophotometric Quantitation of Peroxidase-Stained Protein Bands Following Gel Electrophoresis and the Western Blot Transfer Technique with Respiratory Syncytial Virus," Jour. of Virological Methods 8:265-268 (1984).
Vachereau, A., "Transparency of nitrocellulose membranes with Triton X-114," Electrophoresis 10:524-527 (1989).
Klimov, A.D. et al. "Improved Immunochromatographic Format for Competitive-Type Assays," Clinical Chemistry 41(9):1360 (1995).
Laitinen, M.P.A. and Vuento, M., "Immunochromatographic Assay for Quantification of Milk Progesterone", Acta Chemica Scandinavica, 50:141-145 (1996).
Roberts, M.A. and Durst, R.A., "Investigation of Liposome-Based Immunomigration Sensors for the Detection of Polychlorinated Biphenyls", Anal. Chem., 67:482-491 (1995).
Borque, L., et al., "Automated Quantitative Nephelometric Latex Immunoassay for Determining Ferritin in Human Serum", Journal of Clinical Laboratory Analysis, 6:239-244 (1992).
Birnbaum, S., et al., "Latex-Based Thin-Layer Immunoaffinity chromatography for Quantitation of Protein Analytes", Analytical Biochemistry, 206:168-171 (1992).
Siebert, S.T.A., et al., "Liposome immunomigration field assay device for Alachlor determination", Analytica Chimica Acta, 282:297-305 (1993).
Siebert, S.T.A., et al., "Improved liposome immunomigration strip assay for alachlor determination", Analytica Chimica Acta, 311:309-318 (1995).
Reeves, S.G. and Durst, R.A., "Novel Optical Measurement Approach for the Quantitation of Liposome Immunomigration Assays", Analytical Letters, 28:23347-2362 (1995).
von Olleschik-Elbheim, L., et al., "Quantification of immunological membrane reactions employing a digital desk top scanner and standard graphics software", Jour. of Immun. Methods, 197:181-186, (1996).
Ludlow Jan
University of British Columbia
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