Optical method and apparatus for measuring carbon monoxide in no

Details Optical method and apparatus for measuring carbon monoxide in no Optical method and apparatus for measuring carbon monoxide in no

1998-05-07

2000-07-04

Font, Frank G.

Optics: measuring and testing

Blood analysis

Hemoglobin concentration

356 39, 250343, 250347, 435 29, 435 4, G01N 3348

Patent

active

060846615

ABSTRACT:
Carbon Monoxide (CO) is a colorless, tasteless, and odorless gas which causes asphyxiation by combining with a strong affinity to blood hemoglobin. Unless a patient is quickly identified as having CO poisoning, the patient could face severe medical consequences including death.
This patent describes a reagentless optical method for measuring carboxyhemoglobin (HbCO) in a whole undiluted blood sample that can be obtained from a fingerstick. A battery-operated triple wavelength device measures light transmission at frequencies of 548 nm, 810 nm and 950 nm through a 40 .mu.L sample of undiluted whole blood placed in standard disposable glass capillary tube. Having a portable point-of-care device, for uses by paramedics during an emergency situation, in the emergency room, or in a physician's office, can provide accurate immediate confirmation of CO poisoning.

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patent: 5810723 (1998-09-01), Aldrich
M. Cicale, M.D. "The Usefulness of a New Portable Finger Oximeter" (8G Immunologic Mechanism).
Pieralli et al. "Three wavelength optical oxymetry including the measurement of carboxyhemoglobin concentration" 2331:80-88 (1994).
Vreman et al. "Carbon Monoxide in Blood: An Improved Microliter Blood-Sample Collection System with Rapid Analysis by Gas Chromatography" 30(8): 1382-1386 (1984).

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