Optical measuring method for mevalonic acid

Details Optical measuring method for mevalonic acid Optical measuring method for mevalonic acid

1997-04-08

1998-09-08

Snay, Jeffrey

Chemistry: analytical and immunological testing

Heterocyclic carbon compound

Hetero-o

436129, 436164, 436174, G01N 2165

Patent

active

058044515

ABSTRACT:
Acid is added to a target sample such as urine, blood plasma or serum for converting mevalonic acid contained in the sample to lactone mevalonate, and the sample is irradiated with near infrared Raman excitation light, for determining mevalonic acid by measuring generated Raman scattered light. This method employs no mediatory reaction with simple pretreatment, requires no high-priced measuring apparatus, and can determine mevalonic acid in a short time.

REFERENCES:
patent: 4847198 (1989-07-01), Nelson et al.
patent: 5149641 (1992-09-01), Endo et al.
Spencer, Thomas "Feasibility of an immunoassay for mevalonolactone" Chemical Abstracts, vol. 127, abstract No. 146700r, Sep. 15, 1997.
Patent Abstracts of Japan, vol. 095, No. 009, Oct. 31, 1995 & JP 07-159400 A (S R L:KK), Jun. 23, 1995.

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