Optical isomer separation method

Liquid purification or separation – Processes – Including controlling process in response to a sensed condition

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C210S774000, C023S29500G, C023S296000, C023S297000, C436S171000

Reexamination Certificate

active

07001526

ABSTRACT:
Methods for separation of two optical isomers in a racemate into its constituent isomers by statistical means are described, whereby the saturated racemate solution is first allotted into small samples by means of microfluidic or inkjet techniques to obtain small sample quantities (picoliters to microliters) with one isomer in measurable excess of the other. The samples are then tested by means of spectrophotometers used for measuring Cotton Effects or Circular Dichroism or other related effects which measure the difference in the absorption of right and left circularly polarized light, so that there is a predetermined minimum excess of one enantiomer. Collecting them in three different receptacles then separates the three types of samples. The right and left excess samples are then used in the crystallization process to obtain right or left handed isomers respectively. The third type of sample that is collected is again re-circulated through the sampling process so that right and left excess samples are collected again out of the neutral samples (with less than minimum excess of one kind or the other) and the process continued to crystallize out the two isomers.

REFERENCES:
patent: 4169678 (1979-10-01), Inoue et al.
patent: 4494871 (1985-01-01), Futekov et al.
patent: 5077217 (1991-12-01), Matson et al.
patent: 5196568 (1993-03-01), Zepp et al.
patent: 5504221 (1996-04-01), Yeng et al.
patent: 5593894 (1997-01-01), Purdie
patent: 6002477 (1999-12-01), Hammer
patent: 6123316 (2000-09-01), Biegelsen et al.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Optical isomer separation method does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Optical isomer separation method, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Optical isomer separation method will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3658197

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.