Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1993-08-06
1996-03-05
Scheiner, Toni R.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 732, 435 73, 435 4, 435 6, 435 5, 435 72, 435 721, 436501, 436518, G01N 3353, G01N 33569, C12Q 168, C12Q 170
Patent
active
054967007
ABSTRACT:
The presently disclosed invention relates to a method of rapid detection and identification of microorganisms including bacteria, viruses, rickettsiae and fungi. The method involves staining all microorganisms or fragments thereof in a sample. The stained sample is introduced onto an optical waveguide coated with a capture molecule specific for the microorganism of interest, and the bound microorganism or fragment thereof is then optically detected. For example, detection of B. anthracis and Salmonella was achieved in times of approximately one minute. The sensitivity of this method is on the order of about 3 cells/.mu.l.
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Ligler Frances S.
Shriver-Lake Lisa C.
Wijesuriya Dayaweera C.
McDonnell Thomas E.
Pathak Ajay
Scheiner Toni R.
The United States of America as represented by the Secretary of
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