Optical imaging of breast tissues to enable the detection therei

Surgery – Truss – Pad

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128665, 2503411, 2503581, A61B 600

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active

057996563

ABSTRACT:
A method for detecting the presence of one or more calcifications within a portion of a turbid medium, such as a breast tissue. According to one aspect, the method involves illuminating at least a portion of the turbid medium with light, whereby light emerges from the turbid medium consisting of a ballistic component, a snake-like component and a diffuse component, temporally and/or spatially gating the emergent light to preferentially pass the ballistic and/or snake-like components, using the temporally and/or spatially gated light to form an image of the illuminated portion of the turbid medium, and examining the image for the presence of one or more calcifications. Wavelength difference images may also be used to highlight tumors and calcification regions. The foregoing method may be used to form optical images of breast tissues, with the presence in such images of calcifications suggestive of cancer being used to identify the corresponding breast tissues as good candidates for biopsy and screening for tumors.

REFERENCES:
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Sickles, "Breast Calcifications: Mammographic Evaluation," Radiology, 160:289-93 (1986).
Wang et al., "Ballistic 2-D Imaging Through Scattering Walls Using an Ultrafast Optical Kerr Gate," Science, 253:769-71 (1991).
Yoo et al., "Imaging through a scattering wall using absorption," Opt. Lett., 16:1068-70 (1991).
Egan et al, "Intramammary Calcifications without an Associated Mass in Benign and Malignant Diseases," Radiology, 137:1-7 (1980).

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