Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...
Patent
1997-07-08
2000-11-07
Lankford, Jr., Leon B.
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
435 4, 435 29, 422 8205, 422 8206, 436164, 436172, C12N 500
Patent
active
061435589
ABSTRACT:
Fiberless optical sensors (plasticized PVC, acrylamide or gold particles) are described having a size ranging from between approximately 1 micrometer and 1 nanometer in diameter. The sensors comprise ionophores useful for the detection of intracellular analytes.
REFERENCES:
patent: 4945171 (1990-07-01), Haughland et al.
patent: 5361314 (1994-11-01), Kopelman et al.
patent: 5627922 (1997-05-01), Kopelman et al.
patent: 5691205 (1997-11-01), Kawabata et al.
Tan et al. Science, 258:778, 1992.
Grabar et al., "Preparation and Characterization of Au Colloid Monolayers," Analytical Chemistry 67(4):735-743 (1995).
Freeman et al., "Self-Assembled Metal Colloid Monolayers: An Approach to SERS Substrates," Science 267:1629-1632 (1995).
Grabar et al., "Kinetic Control of Interparticle Spacing in Au Colloid-Based Surfaces: Rational Nanometer-Scale Architecture," J. Am. Chem. Soc. 118:1148-1153 (1996).
Geoghegan et al., "Adsorption of Horseradish Peroxidase, Ovomucoid and Anti-immunoglobulin to Colloidal Gold for the Indirect Detection of Concanavalin A, Wheat Germ Agglutinin and Goat Anti-Human Immunglobulin G on Cell Surfaces at the Electron Microscopic Level: A New Method, Theory and Application," J. of Histochemistry and Cytochemistry 25(11):1187-1200 (1977).
Handley et al., "Colloidal gold-low density lipoprotein conjugates as membrane receptor probes," Proc. Natl. Acad. Sci. USA 78(1):368-371 (1981).
Roe et al., "A Model of Protein-Colloidal Gold Interactions," J. of Histochemistry and Cytochemistry 35(11):1191-1198 (1987).
Handley et al., "Hepatic Binding and Internalization of Low Density Lipoprotein-Gold Conjugates in Rats with 17.alpha.-Ethinylestradiol," J. of Cell Biology 90:778-787 (1981).
Godwin et al., "A Flourescent Zinc Probe Based on Metal-Induced Peptide Folding," J. Am. Chem. Soc. 118:6514-6515 (1996).
Blyth et al., "Sol-Gel Encapsulation of Metalloproteins for the Development of Optical Biosensors for Nitrogen Monoxide and Carbon Monoxide," Analyst 120:2725-2730 (1995).
Dave et al., "Sol-Gel Encapsulation Methods for Biosensors," Analytical Chemistry 66(22):1120A-1127A (1994).
Clark Heather
Kopelman Raoul
Monson Eric
Parus Stephen
Philbert Martin
Lankford , Jr. Leon B.
The Regents of the University of Michigan
LandOfFree
Optical fiberless sensors for analyzing cellular analytes does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Optical fiberless sensors for analyzing cellular analytes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Optical fiberless sensors for analyzing cellular analytes will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1639558