Optical fiber scanner for performing multimodal optical imaging

Surgery – Diagnostic testing – Detecting nuclear – electromagnetic – or ultrasonic radiation

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C600S129000, C600S130000, C250S227260, C250S234000

Reexamination Certificate

active

07616986

ABSTRACT:
An optical fiber scanner is used for multiphoton excitation imaging, optical coherence tomography, or for confocal imaging in which transverse scans are carried out at a plurality of successively different depths within tissue. The optical fiber scanner is implemented as a scanning endoscope using a cantilevered optical fiber that is driven into resonance or near resonance by an actuator. The actuator is energized with drive signals that cause the optical fiber to scan in a desired pattern at successively different depths as the depth of the focal point is changed. Various techniques can be employed for depth focus tracking at a rate that is much slower than the transverse scanning carried out by the vibrating optical fiber. The optical fiber scanner can be used for confocal imaging, multiphoton fluorescence imaging, nonlinear harmonic generation imaging, or in an OCT system that includes a phase or frequency modulator and delay line.

REFERENCES:
patent: 4410235 (1983-10-01), Klement et al.
patent: 4695163 (1987-09-01), Schachar
patent: 4768513 (1988-09-01), Suzuki
patent: 5074642 (1991-12-01), Hicks
patent: 5172685 (1992-12-01), Nudelman
patent: 5247174 (1993-09-01), Berman
patent: 5272330 (1993-12-01), Betzig et al.
patent: 5321501 (1994-06-01), Swanson et al.
patent: 5394500 (1995-02-01), Marchman
patent: 5425123 (1995-06-01), Hicks
patent: 5480046 (1996-01-01), Filas et al.
patent: 5570441 (1996-10-01), Filas et al.
patent: 5703979 (1997-12-01), Filas et al.
patent: 5715337 (1998-02-01), Spitzer et al.
patent: 5727098 (1998-03-01), Jacobson
patent: 6046720 (2000-04-01), Melville et al.
patent: 6069698 (2000-05-01), Ozawa et al.
patent: 6091067 (2000-07-01), Drobot et al.
patent: 6134003 (2000-10-01), Tearney et al.
patent: 6161035 (2000-12-01), Furusawa
patent: 6191862 (2001-02-01), Swanson et al.
patent: 6211904 (2001-04-01), Adair et al.
patent: 6294775 (2001-09-01), Seibel et al.
patent: 6327493 (2001-12-01), Ozawa et al.
patent: 6370422 (2002-04-01), Richards-Kortum et al.
patent: 6485413 (2002-11-01), Boppart et al.
patent: 6549801 (2003-04-01), Chen et al.
patent: 6687010 (2004-02-01), Horii et al.
patent: 7023558 (2006-04-01), Fee et al.
patent: 7072046 (2006-07-01), Xie et al.
patent: 7158234 (2007-01-01), Uchiyama et al.
patent: 7170610 (2007-01-01), Knuttel
patent: 7189961 (2007-03-01), Johnston et al.
patent: 7349098 (2008-03-01), Li
patent: 2001/0055462 (2001-12-01), Seibel
patent: 2002/0064341 (2002-05-01), Fauver et al.
patent: 2003/0004412 (2003-01-01), Izatt et al.
patent: 2003/0142934 (2003-07-01), Pan et al.
patent: 2004/0015049 (2004-01-01), Zarr
patent: 2004/0181148 (2004-09-01), Uchiyama et al.
patent: 2005/0111009 (2005-05-01), Keightley et al.
patent: 2005/0168751 (2005-08-01), Horii et al.
patent: 2006/0126064 (2006-06-01), Bambot et al.
patent: 2006/0187462 (2006-08-01), Srinivasan et al.
patent: 2006/0202115 (2006-09-01), Lizotte et al.
patent: 2007/0038119 (2007-02-01), Chen et al.
patent: 2007/0088219 (2007-04-01), Xie et al.
patent: 2007/0129601 (2007-06-01), Johnston et al.
patent: 2007/0213618 (2007-09-01), Li et al.
patent: 2008/0004491 (2008-01-01), Karasawa
patent: 0 713 672 (1996-05-01), None
patent: 0 520 388 (1996-09-01), None
patent: 1 142 529 (2001-10-01), None
patent: 0 712 032 (2001-12-01), None
patent: 2001174744 (2001-06-01), None
patent: WO 01/97902 (2001-12-01), None
Bing Qi et al. “Dynamic Focus Control in High-Speed Optical Coherence Tomography Based on a Microelectromechanical Mirror.” Optics Communications 232 (2004) 123-128. <www.elsevier.com/locate/optcom>.
D. Huang, E.A. Swanson, C.P. Lin, J.S. Schuman, W.G. Stinson, W. Chang, M.R. Hee, T. Flotte, K. Gregory, C.A. Puliafito, and J.G. Fujimoto. “Optical Coherence Tomography.” Science, 254, 1178-1181 (1991).
W. Drexler, U. Morgner, F.X. Kartner, C. Pitris, S.A. Boppart, X.D. Li, E.P. Ippen, and J.G. Fujimoto. “In vivo ultrahigh-resolution optical coherence tomography.” Optics Letters, 24, 1221-1223 (1999).
M. Ohmi, T. Kurata, M. Sekimoto, and M. Haruna. “Quasi in-focus optical coherence tomography.” Japanese Journal of Applied Physics Part 1—Regular Papers Short Notes & Review Papers, 43, 845-849 (2004).
Z.P. Chen, T.E. Milner, D. Dave, and J.S. Nelson, “Optical Doppler tomographic imaging of fluid flow velocity in highly scattering media.” Optics Letters, 22, 64-66 (1997).
J.M. Schmitt, S.L. Lee, and K.M. Yung. “An optical coherence microscope with enhanced resolving power in thick tissue.” Optics Communications, 142, 203-207 (1997).
F. Lexer, C.K. Hitzenberger, W. Drexler, S. Molebny, H. Sattmann, M. Sticker, and A.F. Fercher. “Dynamic coherent focus OCT with depth-independent transversal resolution.” Journal of Modern Optics, 46, 541-553 (1999).
B. Qi, A.P. Himmer, L.M. Gordon, X.D.V. Yang, L.D. Dickensheets, and I.A. Vitkin, “Dynamic focus control in high-speed optical coherence tomography based on a microelectromechanical mirror.” Optics Communications, 232, 123-128 (2004).
V.X.D. Yang, N. Munce, J. Pekar, M.L. Gordon, S. Lo, N.E. Marcon, B.C. Wilson, and I.A. Vitkin, “Micromachined array tip for multifocus fiber-based optical coherence tomography.” Optics Letters, 29, 1754-1756 (2004).
X.M. Liu, M.J. Cobb, Y.C. Chen, M.B. Kimmey, and X.D. Li. “Rapid-scanning forward-imaging miniature endoscope for real-time optical coherence tomography.” Optics Letters, 29, 1763-1765 (2004).
A.G. Podoleanu, J.A. Rogers, and D.A. Jackson. “Three dimensional OCT images from retina and skin.” Optics Express, 7, 292-298 (2000).
Y.C. Chen and X.D. Li. “Dispersion management up to the third order for real-time optical coherence tomography involving a phase or frequency modulator.” Optics Express, 12, 5968-5978 (2004).
G.J. Tearney, M.E. Brezinski, J.F. Southern, B.E. Bouma, M.R. Hee, and J.G. Fujimoto. “Determination of the Refractive-Index of Highly Scattering Human Tissue by Optical Coherence Tomography.” Optics Letters, 20, 2258-2260 (1995).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Optical fiber scanner for performing multimodal optical imaging does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Optical fiber scanner for performing multimodal optical imaging, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Optical fiber scanner for performing multimodal optical imaging will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4131043

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.