Optical fiber pH microsensor and method of manufacture

Chemical apparatus and process disinfecting – deodorizing – preser – Analyzer – structured indicator – or manipulative laboratory... – Means for analyzing liquid or solid sample

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

422 8206, 385 12, 128634, 8647, G01N 2100, C09B 6910

Patent

active

052778720

ABSTRACT:
The optical fiber pH microsensor includes an optical fiber having a portion of the surface of a light conducting core covered with a layer of a pH sensitive dye material. The dye material is covalently bonded to a polymeric matrix which is in turn covalently bonded to the optical fiber core to prevent leaching of the indicator dye material during extended use. The dye material is crosslinked in situ over the tip of the optical fiber to yield a hydrophilic, ion permeable pH sensor which can be used intravascularly to monitor blood pH.

REFERENCES:
patent: Re31879 (1985-05-01), Lubbers et al.
patent: 4003707 (1977-01-01), Lubbers et al.
patent: 4029598 (1977-06-01), Neisios et al.
patent: 4194877 (1980-03-01), Peterson
patent: 4200110 (1980-04-01), Peterson et al.
patent: 4399099 (1983-08-01), Buckles
patent: 4548907 (1985-10-01), Seitz et al.
patent: 4560248 (1985-12-01), Cramp et al.
patent: 4581337 (1986-04-01), Frey et al.
patent: 4657736 (1987-04-01), Marsoner et al.
patent: 4712865 (1987-12-01), Hsu et al.
patent: 4785814 (1988-11-01), Kane
patent: 4798738 (1989-01-01), Yafuso et al.
patent: 4801655 (1989-01-01), Murray, Jr. et al.
patent: 4803049 (1989-02-01), Hirschfeld et al.
patent: 4842783 (1989-06-01), Blaylock
patent: 4886338 (1989-12-01), Yafuso et al.
patent: 4906249 (1990-03-01), Fogt et al.
patent: 4925268 (1990-05-01), Iyer et al.
patent: 4933416 (1990-06-01), Gillis et al.
patent: 4999306 (1991-03-01), Yafuso et al.
patent: 5015843 (1991-05-01), Seitz et al.
patent: 5019350 (1991-05-01), Rhum et al.
patent: 5081041 (1992-01-01), Yafuso et al.
Thomas P. Jones and Marc D. Porter, "Optical pH Sensor Based on the Chemical Modification of a Porous Polymer Film", Anal. Chem. 1988, 60, 404-406.
Gehrich, et al., "Optical Fluorescence and Its Application to an Intravascular Blood Gas Monitoring System", Transactions on Biomedical Engineering, vol. BME-33, No. 2, Feb. 1986.
Munkholm et al., "Polymer Modification of Fiber Optic Chemical Sensors As a Method of Enhancing Fluorescence Signal for pH Measurement", Anal. Chem. 1986, 58, 1427-1430.
Offenbacher, et al. "Fluorescence Optical Sensors for Continuous Determination of Near-Neutral pH Values", Sensors and Actuators, 9 (1986) 73-84.
Peterson, et al. "Fiber Optic pH Probe for Physiological Use", Anal. Chem. 1980, 52, No. 6.
Zhujun, et al. "A Fluorescence Sensor for Quantifying pH in the Range from 6.5 to 8.5", Analytica Chimica Acta, 160, 1984, 47-55.
Saari, Linda, "pH Sensor Based on Immobilized Fluoresceinamine" Anal. Chem. 1982, 54, 821-823.
Zhujun et al. "Poly(Vinyl Alcohol) as a Substrate for Indicator Immobilization for Fiber-Optic Chemical Sensors" Anal. Chem. 1989, 61, 202-205.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Optical fiber pH microsensor and method of manufacture does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Optical fiber pH microsensor and method of manufacture, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Optical fiber pH microsensor and method of manufacture will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1629317

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.