Optical cell and optical detection systems light absorption

Optics: measuring and testing – Sample – specimen – or standard holder or support – Fluid containers

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356440, 356344, G01N 2105, G01N 1502

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active

054145082

ABSTRACT:
An optical cell or an optical detection system, of a simple structure having a small light path length, such as, for example, an optical cell having a light path length equal to that of a capillary. Light incidence and exit surfaces of the optical cell are each formed by a half transmitting mirror, and light is made incident on the optical cell in a direction perpendicular to the cell. The reflectance of the half transmitting mirror formed at the incidence surface is set smaller than that of the half transmitting mirror formed at the exit surface. The said optical cell or optical detection system is used as an optical detector portion of a sample separation and detection system which is for separation and detection of a sample using a liquid chromatography system or an electrophoresis system. Because of multi-reflection of light between both half transmitting mirrors, an effective increase of absorbance is obtained and even a sample whose absorbance is not higher than the noise level can be detected easily in high sensitivity. Further, since even a low concentration of sample does not cause lowering in the intensity of fluorescence, it is possible to detect both absorbance and fluorescence simultaneously.

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Wang et al., "Nanoliter-Scale Multireflection Cell for Absorption Detection in Capillary Electrophoresis", American Chemical Society, vol. 63, No. 14 (1991) 1372-1376.
Gould, John H., "Construction and Use of Reflecting Multiple-Pass Absorption Cells for the Ultraviolet, Visible and Near Infrared", Applied Spectroscopy, Jan./Feb. 1971, vol. 25, No. 1, pp. 103-105.

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