Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1992-04-23
1998-12-08
Ketter, James
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 71, 204403, C12Q 168, G01N 3353, G01N 2726
Patent
active
058467084
ABSTRACT:
A method and apparatus are disclosed for identifying molecular structures within a sample substance using a monolithic array of test sites formed on a substrate upon which the sample substance is applied. Each test site includes probes formed therein to bond with a predetermined target molecular structure or structures. A signal is applied to the test sites and certain electrical, mechanical and/or optical properties of the test sites are detected to determine which probes have bonded to an associated target molecular structure.
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Burke Barry E.
Eggers Mitch D.
Ehrlich Daniel J.
Hogan Michael E.
Hollis Mark A.
Brosca John S.
Ketter James
Massachusetts Institiute of Technology
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