Optical amplification of molecular interactions using liquid...

Chemical apparatus and process disinfecting – deodorizing – preser – Analyzer – structured indicator – or manipulative laboratory... – Means for analyzing liquid or solid sample

Reexamination Certificate

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C422S051000, C422S051000, C422S068100, C422S082010, C435S007100, C435S007400, C436S501000, C436S524000, C436S528000, C436S805000

Reexamination Certificate

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06852285

ABSTRACT:
Interactions between molecules which are components of self-assembled monolayers and other molecules can be amplified and transduced into an optical signal through the use of a mesogenic layer. The invention provides a device and methods for detecting analytes. The device comprises a substrate onto which a self-assembled monolayer is attached and a mesogenic layer which is anchored by the self-assembled monolayer. The mesogenic layer undergoes a change in conformation in response to the molecular interaction.

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