Drug – bio-affecting and body treating compositions – Topical body preparation containing solid synthetic organic... – Ophthalmic preparation
Patent
1996-08-14
1999-04-20
Mullis, Jeffrey
Drug, bio-affecting and body treating compositions
Topical body preparation containing solid synthetic organic...
Ophthalmic preparation
424 7823, 424 7836, A61K 3116, A61K 31395
Patent
active
058956450
ABSTRACT:
An ophthalmic artificial tear solution is described for treating irritation and dryness of the eyes with a formulation that includes polyvinylpyrrolidone, a preservative such as benzalkonium chloride, glycerin and hydroxypropyl methylcellulose, wherein the composition is an aqueous solution having isotonic properties with respect to the eye. The ophthalmic solution of the invention is characterized as having a low viscosity, preferably less than 5 cps, and a low surface tension, preferably less than 40 dynes/cm, wherein wettability, retainability and comfort of the user are enhanced.
REFERENCES:
patent: 3311577 (1967-03-01), Rankin
patent: 3549747 (1970-12-01), Krezanowski et al.
patent: 3856919 (1974-12-01), Rankin
patent: 3920810 (1975-11-01), Rankin
patent: 3947573 (1976-03-01), Rankin
patent: 3987163 (1976-10-01), Rankin
patent: 4013576 (1977-03-01), Loshaek
patent: 4029817 (1977-06-01), Blanco et al.
patent: 4039662 (1977-08-01), Hecht et al.
patent: 4120949 (1978-10-01), Bapatla et al.
patent: 4421748 (1983-12-01), Trager et al.
patent: 4432964 (1984-02-01), Shell et al.
patent: 4438123 (1984-03-01), Smith
patent: 4460573 (1984-07-01), Huth et al.
patent: 4470965 (1984-09-01), Wolf et al.
patent: 4626292 (1986-12-01), Sherman
patent: 4744980 (1988-05-01), Holly
patent: 4910225 (1990-03-01), Ogawa et al.
patent: 5061714 (1991-10-01), Tadokoro et al.
patent: 5106615 (1992-04-01), Dikstein
patent: 5141665 (1992-08-01), Sherman
patent: 5264449 (1993-11-01), Albaugh
patent: 5453435 (1995-09-01), Raheja et al.
patent: 5703047 (1997-12-01), Wilson
AV Tiffany, Winter and Bliss, Current Eye Research, vol. 8, Nov. 5, 1989, "Tear Film Stability and Tear Surface Tension", pp. 507-515.
AW 53 Fed. Reg. 7076 (Mar. 1988), 21 CFR Parts 349 and 369, Opthalmic Drug Products for Over-the-Counter Human Use; Final Monograph; Final Rule.
Dabrowski Henry P.
Lever, Jr. O. William
Salpekar Anil
Bausch & Lomb Incorporated
Konkol Chris P.
Mullis Jeffrey
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