Opsonin-enhanced cells, and methods of modulating an immune resp

Details Opsonin-enhanced cells, and methods of modulating an immune resp Opsonin-enhanced cells, and methods of modulating an immune resp

1997-03-27

1999-09-14

Hutzell, Paula K.

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

424 937, 435325, 514 12, 514 21, A61K 3800, C12N 900, C12N 506, A01N 6300

Patent

active

059519762

ABSTRACT:
Disclosed are methods and compositions wherein opsonin-enhanced cells, that is, cells which have been 1) modified so as to express an opsonin from a recombinant nucleic acid, 2) modified so as to express higher levels of an endogenous opsonin, or 3) mixed with an exogenous opsonin, when administered to a subject, modulate the immune response in the recipient to a selected antigen or antigens contained in or attached to the cells.

REFERENCES:
patent: 5270199 (1993-12-01), Ezekowitz

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