Opposable-element assay device employing unidirectional flow

Details Opposable-element assay device employing unidirectional flow Opposable-element assay device employing unidirectional flow

1997-01-29

1999-03-09

Chin, Christopher L.

Chemistry: analytical and immunological testing

Involving diffusion or migration of antigen or antibody

422 56, 422 57, 422 58, 422 61, 435 79, 435 792, 4352871, 4352872, 4352877, 4352878, 4352879, 435805, 435810, 435970, 435975, 436518, 436528, 436530, 436169, 436805, 436808, 436810, G01N 33558

Patent

active

058799516

ABSTRACT:
An assay device for the performance of assays for analytes, particularly those of biological interest, provides for improved efficiency and sensitivity by reducing background. The assay device performs an immunochromatographic assay and also provides a wash to remove unbound labeled specific binding partner and thereby reduce the background. Assay devices according to the present invention can use either a directly visible label such as a metal sol label or an enzyme label. One embodiment of assay devices according to the present invention is particularly suitable for assay of analytes in whole blood samples. The present invention also encompasses test kits and methods of use of the assay devices.

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