Ophthmalic irrigating solution

Details Ophthmalic irrigating solution Ophthmalic irrigating solution

1981-10-05

1984-04-17

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Fermentate of unknown chemical structure

Having a known elemental analysis

424128, 424153, 424154, 424156, A61K 3300, A61K 3314, A61K 3306, A61K 3310

Patent

active

044434324

ABSTRACT:
An ophthalmic irrigating solution useful for irrigating the human eye contains sodium, potassium, magnesium, calcium, chloride, and bicarbonate ions as well as dextrose and glutathione in proportions consistent with the osmotic stability and continued metabolism of the endothelial cells. The irrigating solution is prepared by mixing a first basic solution which provides the bicarbonate and a second acidic solution which provides the calcium, magnesium, dextrose and glutathione. The first and second solutions may be stored as stable, sterile solutions for extended periods of time and mixed within 24 hours of use.

REFERENCES:
patent: 3821368 (1974-06-01), Reynolds
patent: 3843782 (1974-10-01), Krezanoski et al.
patent: 3897550 (1975-07-01), Reynolds
patent: 3978212 (1976-08-01), Barna
B. E. McCarey et al., Investigative Ophthalmology, Jun. 1973, pp. 410-417, vol. 2, No. 6.
Edelhauser et al., Laboratory Sciences 93 Aug. 1975, pp. 648-657.
Edelhauser, Archives of Ophthalmology, Mar. 1978, vol. 96, pp. 516-520.
McEnerney et al., Ophthalmic Surgery, vol. 9, No. 1, Feb. 1973, pp. 66-72.

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