Ophthalmological collagen coverings

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

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424428, 424429, 128DIG8, 530356, 623 4, 514912, 514955, A61F 214

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050948563

ABSTRACT:
Ophthalmologic collagen coverings derived from animal eyes and a process preparing such coverings comprising treatment of a fibrous tunic of an animal eye with an alkali metal hydroxide in a saturated solution of a salt of an alkali metal, followed by neutralization, dissolution in an aqueous solution of an organic acid, purification of the resulting solution of collagen by dialysis against a buffer solution while bringing the solution of collagen to a pH of 4.5 to 7.5 and drying the thus-obtained solution of collagen simultaneously with shaping spherical coverings therefrom.

REFERENCES:
patent: 3553299 (1971-01-01), Thiele et al.
patent: 3637642 (1972-01-01), Fujii
Stryer, Biochemistry, 2nd Ed., W. H. Freeman and Co. 1981, pp. 18-19.

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