Ophthalmic solutions

Details Ophthalmic solutions Ophthalmic solutions

1981-09-28

1983-10-04

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Lymphokine

424 78, 424329, A61K 3174, A61K 3179, A61K 3114

Patent

active

044077912

ABSTRACT:
This invention relates to the quaternary ammonium salt, .alpha.-4-[-tris (2-hydroxyethyl) ammonium chloride-2-butenyl] poly[1-dimethyl ammonium chloride-2-butenyl]-w-tris (2-hydroxyethyl) ammonium chloride, providing aqueous disinfecting solutions for contact lenses as well as a preservative for ocular solutions including contact lens treating solutions.

REFERENCES:
patent: 3639576 (1972-02-01), Kaspar et al.
patent: 3882036 (1975-05-01), Krezanoski et al.
patent: 3961042 (1976-06-01), Green et al.
patent: 3966904 (1976-06-01), Green et al.
patent: 4005193 (1977-01-01), Green et al.
patent: 4012446 (1977-03-01), Green et al.
patent: 4025945 (1977-05-01), Green et al.
patent: 4027020 (1977-05-01), Green et al.
Product Bulletin (LRSBD 12177) of the Onyx Chemical Company, New York, N.Y.
Letter from Petrocci to Randeri Dated Oct. 19, 1981.
Petrocci et al., 1978 "Quaternary Ammonium Antimicrobial Compounds: Old and New" Developments in Industrial Microbiology 20: 11-14.
Richardson et al., 1978, "The Interaction of Preservatives with Polyhydroxy-Ethylmethacrylate(polyHEMA)", J. Pharm. Pharmac., 30: 469-475.
Kaspar, 1976 "Binding Characteristics and Microbiological Effectiveness of Preservatives" Australian Journal of Optometry, pp. 3-8.
Refojo, 1972, "Reversible Binding of Chlorhexidine Gluconate to Hydrojel Contact Lenses" Contact and Intraocular Lens Med. J. , 2 pp. 47-56.

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