Ophthalmic pharmaceutical composition containing N-acetyl-cystei

Drug – bio-affecting and body treating compositions – Designated organic nonactive ingredient containing other... – Solid synthetic organic polymer

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514912, 514913, 514914, 514915, 424 7804, A61K 31195, A61K 3174

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active

054880696

ABSTRACT:
An ophthalmic pharmaceutical composition containing an association of N-acetyl-cysteine and polyvinylalcohol useful for the treatment of keratoconjunctivitis sicca.

REFERENCES:
patent: 4120949 (1978-10-01), Bapatla et al.
patent: 4131651 (1978-12-01), Shah et al.
patent: 4409205 (1983-10-01), Shively
patent: 4883658 (1984-11-01), Holly
Acta Ophthamol., vol. 55, No. 1, 1977, pp. 23-034, M. S. Norn `Effects of ophthalmic vehicles on the stability of the precorneal film`.
Curr. Ther. vol. 28, No. 9, 1987, pp. 99-108, T. R. Ellingham `The dry eye. Modern management`.
Patent Abstracts of Japan, vol. 8, No. 114 (C-225) 1984 of JP-A-59 028 498 (Yatoron).
Drug Ther. Bull., vol. 23, No. 21, 1985, pp. 81-82, `Management of the dry eye`.
The Merck Index--XI Ed.--No. 7562, p. 1208, "Polyvinyl Alcohol".
The Merck Index--XI Ed., No. 82, p. 14, "Acetylcysteine".
Opthalmic Drug Delivery, Biopharmaceutical, Technological and Clinical Aspects, vol. 11, (1987), M. S. Saettone, et al., pp. 37-47, "Semiology Of The Tear Film."

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