Drug – bio-affecting and body treating compositions – Topical body preparation containing solid synthetic organic... – Ophthalmic preparation
Reexamination Certificate
2005-02-08
2005-02-08
Azpuru, Carlos A. (Department: 1615)
Drug, bio-affecting and body treating compositions
Topical body preparation containing solid synthetic organic...
Ophthalmic preparation
Reexamination Certificate
active
06852311
ABSTRACT:
Ophthalmic ointments for treating infective eye diseases which are particularly effective against infective eye diseases caused by methicillin-resistantStaphylococcus aureus(MRSA) or methicillin-resistantStaphylococcus epidermidis(MRSE) and contain as the active ingredient from 0.01 to 5.0% of vancomycin hydrochloride. Compared with intravenous administration, topical administration of these ophthalmic ointments is accompanied with no problem of the occurrence of side effects such as renal toxicity and thus enables the maintenance of a therapeutically effective concentration.
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Hanna, et al “Delivery of Antibiotics to the Eye”, Life Science, 1980.*
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Eiferman, et al. “Methicillin-resistantStaphylococcus aureuscorneal ulcers” Annals of Ophthalmology, 1991.
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Hanna, et al. “Delivery of antibiotics to the Eye” Life Science, 1980.
Hanazome Isao
Kasama Toshio
Noto Mitsuru
Oguro Susumu
Tatekawa Rena
Azpuru Carlos A.
Crowell & Moring LLP
TOA Pharmaceutical Co., Ltd.
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