Ophthalmic drug delivery system utilizing thermosetting gels

Details Ophthalmic drug delivery system utilizing thermosetting gels Ophthalmic drug delivery system utilizing thermosetting gels

1983-05-16

1984-10-02

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

424 85, 424 94, 424114, 424116, 424177, 424180, 424181, 424209, 424211, 424220, 424221, 424224, 424230, 424238, 424243, 424246, 42424851, 424251, 424253, 424254, 424256, 424258, 424263, 424265, 424267, 424270, 424271, 424273P, 424273R, 424274, 424275, 424283, 424285, 424300, 424309, 424311, 424313, 424317, 424321, 424322, 424324, 424326, 424330, 424343, A61K 3174, A61K 3170, A61K 31135, A61K 3154, A61K 31415, A61K 31435, A61K 3119, A61K 3166

Patent

active

044747519

ABSTRACT:
This invention describes the application of selected polymers as novel drug delivery systems which use the body temperature and pH to induce a liquid to gel transition of the polymer which contains a drug or therapeutic agent therein. The goal of such a delivery system is to achieve a greater degree of bioavailability or sustained concentration of a drug.

REFERENCES:
patent: 2979528 (1961-04-01), Lundsted
patent: 3711604 (1973-01-01), Colodney et al.
patent: 3884826 (1975-05-01), Phares et al.
patent: 4188373 (1980-02-01), Kresanski
Journal of Pharm. & Pharmacology-"Novel Poloxamer & Poloxamine Hydrogels: Swelling & Drug Release" vol. 32, p. 5p, (1980), by A. Saden, A. J. Florence, T. L. Whateley.

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