Drug – bio-affecting and body treating compositions – Topical body preparation containing solid synthetic organic... – Ophthalmic preparation
Patent
1996-08-07
1998-07-07
Azpuru, Carlos
Drug, bio-affecting and body treating compositions
Topical body preparation containing solid synthetic organic...
Ophthalmic preparation
514779, 514912, A61K 3174, A61K 4736
Patent
active
057764450
ABSTRACT:
The present invention relates to formulations particularly well suited for use as delivery systems in the delivery of an active agent to the eye. The formulations comprise an alginate having a particular proportion of guluronic acid.
REFERENCES:
patent: 4861760 (1989-08-01), Mazuel et al.
patent: 5139783 (1992-08-01), Handjani et al.
patent: 5144016 (1992-09-01), Skjak-Braek et al.
patent: 5147648 (1992-09-01), Bannert
patent: 5200180 (1993-04-01), Bannert
patent: 5336668 (1994-08-01), Francesco et al.
"The Controlled Release of Prednisolone Using Alginate Gel"; S. Sugawara, T. Imai and M. Otagiri; Pharmaceutical Research, vol. 11, pp. 272-277, 1994.
"PS-60: A New Gel-Forming Polysaccharide"; R. Moorhouse, G.T. Colegrove, P.A. Sandford, J.K. Baird and K.S. Kang; Solution Properties of Polysaccharides; ACS Symposium Series 150; American Chemical Society, Washington, D.C.; pp. 111-124, 1981.
"Effect of poloxamer 407 gel on the miotic activity of pilocarpine nitrate in rabbits"; Susan C. Miller and Maureen D. Donovan; International Journal of Pharmaceutics, vol. 12, Nos. 2-3, pp. 147-152; 1982.
"Diffusional Systems for Controlled Release of Drugs to the Eye"; John W. Shell, Ph.D. and Richard W. Baker, Ph.D.; Annals of Ophthalmology; vol. 6, No. 10, pp. 1037-1045, Oct. 1974.
"Ocular Therapy With Nanoparticulate Systems For Controlled Drug Delivery"; Robert Gurny, Tor Boye and Houssam Ibrahim; Journal of Controlled Release; Special Issue, pp. 353-361, 1985.
"Gelrite: A novel, ion-activated, in-situ gelling polymer for ophthalmic vehicles. Effect on bioavailability of timolol"; A. Rozier, C. Mazuel, J. Grove and B. Plazonnet; International Journal of Pharmaceutics; vol. 57, No. 2, pp. 163-168, Dec. 22, 1989.
Olav Simsrod, "Molecular Basis for some Physical Properties of Alginates in the Gel State," Faraday Discuss. Chem. Soc., vol. 57, 1974, pp. 263-281.
Ji et al., Chemical Abstracts, vol. 102, #21275.
Cohen Smadar
Lobel Esther
Azpuru Carlos
Teva Pharmaceutical Industries Ltd.
The Ben Gurion University of the Negev
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