Ophthalmic composition for treating dry eye

Drug – bio-affecting and body treating compositions – Inorganic active ingredient containing – Aluminum – calcium or magnesium element – or compound containing

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424682, 424687, 424696, 424484, 424489, 424500, 424502, 514912, 514914, 514915, 514951, A61K 4700, A61K 914

Patent

active

055957641

ABSTRACT:
An ophthalmologic composition therapeutic in the treatment of dry eye syndrome is disclosed. The composition is comprised of a minimally soluble salt of calcium that has been finely divided into particles having a mean diameter of 10 to 60 microns. The calcium salt particles are suspended within a pharmacologically acceptable carrier such as petrolatum or physiological saline. The composition is delivered to the ocular surface in an amount and for a time sufficient to alleviate the symptoms of dry eye.

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Lemp, 1972. Annals of Ophthalmology 4:15, "Ophthalmic Polymers as Ocular Wetting Agents," pp. 15-20.
Lemp, 1973, International Ophthalmology Clinics 13:221, "Artificial Tear Solutions", pp. 221-229; in Holly et al.(eds.), The Preocular Tear Film and Dry Eye Syndromes, Little Brown and Co., Boston, 1973.
Physician's Desk Reference for Ophthalmology, 16 Edition, 1988 pp. 9,11,12,and 13.
PTS Newsletter Database. Bausch & Lomb Dry Eye Therapy Lubricating Eye Drops, Dialog file 636, 01261920, (1991).

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