Open channel solid phase extraction systems and methods

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Separation or purification

Reexamination Certificate

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C530S415000, C210S656000, C422S070000

Reexamination Certificate

active

07667010

ABSTRACT:
The invention provides, inter alia, methods of extracting an analyte from a solution comprising the steps of: passing a solution containing an analyte through an extraction channel having a solid phase extraction surface, whereby analyte adsorbs to the extraction surface of said extraction channel; purging bulk liquid from said extraction channel; and eluting the analyte by passing a desorption solvent through the channel. The invention further provides reagents, columns and instrumentation related to this and other methods.

REFERENCES:
patent: 2002/0139751 (2002-10-01), Zhang et al.
patent: 2004/0126890 (2004-07-01), Gjerde et al.
patent: 2004/0224329 (2004-11-01), Gjerde et al.
patent: 2004/0224425 (2004-11-01), Gjerde et al.
Zhang and Horvath, “Capillary electrophoresis of proteins in dextran-coated columns”, Electrophoresis 24: 115-120 (2003).

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