Open channel solid phase extraction systems and methods

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Separation or purification

Reexamination Certificate

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C210S656000, C422S070000

Reexamination Certificate

active

07151167

ABSTRACT:
The invention provides, inter alia, methods of extracting an analyte from a solution comprising the steps of: passing a solution containing an analyte through an extraction channel having a solid phase extraction surface, whereby analyte adsorbs to the extraction surface of said extraction channel; and eluting the analyte by passing a desorption solution through the channel, wherein the method includes a step wherein a multiple-pass solution is passed through at least some substantial portion of the extraction channel at least twice. Non-limiting examples multiple-pass solutions include a solution containing an analyte, a wash solution and/or a desorption solution.

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