Open chain rifamycin derivatives

Details Open chain rifamycin derivatives Open chain rifamycin derivatives

1991-04-12

1992-03-31

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514183, 544368, 540459, C07D49812

Patent

active

051008947

ABSTRACT:
Compounds of the general formula: ##STR1## in which R is a lower alkyl group, and R.sub.1 is a tri-lower alkylmethylcarbonyl group, the structure elements --A.sub.1 --A.sub.2 --, A.sub.3 --A.sub.4 -- or A.sub.5 --A.sub.6 -- each represent ethylene or vinylene, or the elements --A.sub.1 --A.sub.2 -- and --A.sub.3 --A.sub.4 -- each represent ethylene and --A.sub.5 --A.sub.6 -- represents vinylene, their optical isomers and their salts exhibit valuable pharmaceutical properties.

REFERENCES:
patent: 4002754 (1977-01-01), Cricchio et al.
patent: 4005077 (1977-01-01), Bickel et al.
patent: 4876258 (1989-10-01), Kump et al.
patent: 4916126 (1990-04-01), Traxler et al.
patent: 4918066 (1990-04-01), Kump et al.
patent: 5003070 (1991-03-01), Kump et al.
Taguichi et al., Chem. Pharm. Bull. vol. 33, No. 5 pp. 2133-2135 (1985).

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