Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1994-10-31
1998-05-26
Housel, James C.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
4242001, 435 691, 435 693, 530350, 536 231, 536 237, A61K 39102, A61K 3902, C12P 2106, C07K 100
Patent
active
057561052
ABSTRACT:
Opacity associated proteins and DNA encoding the same are provided by the present invention. Opacity associated proteins are membrane proteins of H. influenzae which are useful as immunogens in vaccines against infection by H. influenzae. Recombinant cells transformed with DNA encoding opacity associated proteins and vectors encoding the same are also provided and are useful in and for the preparation of vaccines against H. influenzae infection. Antibodies against opacity associated proteins are also described. Methods of detecting H. influenzae in a sample and methods of immunizing mammals against H. influenzae are also provided.
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Children's Hospital of Philadelphia
Housel James C.
Shaver Jennifer
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