One step thromboresistant lubricious coating

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428332, 4284231, 4284233, 4284242, 4284248, 604265, B32B 2740

Patent

active

056459319

ABSTRACT:
Articles having lubricious polymeric coatings are disclosed. The coatings are comprised of a substantially homogeneous composite of poly(ethylene oxide) and polyisocyanate applied in a single step operation as a mixture in an inert solvent. The coating is believed to form a polymeric complex through an in-situ hydrolysis of the polyisocyanate in the system without substantial crosslinking to form polyurethanes. The polymeric complexes have particular utility in providing medical devices such as catheters with a high degree of abrasion resistance and lubricity when in contact with bodily fluids.

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